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The Science of Eating for Health, Fat Loss & Lean Muscle | Dr. Layne Norton

Food

My guest is Layne Norton, Ph.D. — one of the world’s foremost experts in nutrition, protein metabolism, muscle gain and fat loss. We discuss the science of energy utilization and balance, the efficacy of different diets (e.g. ketogenic, vegan, vegetarian, carnivore, omnivore) and how best to build lean muscle mass and lose fat. We also discuss optimal protein and fiber intake, the best sources of protein, the correlation between appetite, satiety signals and exercise along with male- and female-specific needs. Dr. Norton also explains how to support a healthy gut microbiome and offers insight into sugar and artificial sweeteners, processed, cooked and raw foods, supplements, seed oils and the relationship of LDL/HDL levels to cardiovascular health. This episode serves as a master class in nutrition, metabolism and exercise and is sure to benefit people of all ages with different health and fitness goals. Read the episode show notes: https://go.hubermanlab.com/btAPVk4 *Thank you to our sponsors* AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://www.drinklmnt.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman *Huberman Lab Premium* https://hubermanlab.com/premium *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://hubermanlab.com Newsletter: https://hubermanlab.com/neural-network *Dr. Layne Norton* BioLayne: https://biolayne.com Carbon app: https://joincarbon.com REPS (Research Explained in Practical Summaries): https://biolayne.com/reps Books: https://biolaynestore.com/collections/accessories *Timestamps* 00:00:00 Dr. Layne Norton, Nutrition & Fitness 00:02:53 LMNT, ROKA, InsideTracker, Momentous 00:06:50 Calories & Cellular Energy Production 00:12:35 Energy Balance, Food Labels, Fiber 00:15:19 Resting Metabolic Rate, Thermic Effect of Food 00:19:04 Exercise & Non-Exercise Activity Thermogenesis (NEAT) 00:25:49 Losing Weight, Tracking Calories, Daily Weighing 00:29:24 Post-Exercise Metabolic Rate, Appetite 00:35:04 AG1 (Athletic Greens) 00:36:19 Exercise & Appetite, Calorie Trackers, Placebo Effects & Beliefs 00:43:46 Exercise & Satiety Signals, Maintain Weight Loss & Identity 00:56:32 Weight Loss & Maintenance, Diet Adherence 01:03:33 Restrictive Diets & Transition Periods 01:08:03 Gut Health & Appetite 01:16:23 Tool: Supporting Gut Health, Fiber & Longevity 01:23:59 LDL, HDL & Cardiovascular Disease 01:30:31 Leucine, mTOR & Protein Synthesis 01:37:31 Tool: Daily Protein Intake & Muscle Mass 01:44:24 Protein & Fasting, Lean Body Mass 01:55:38 Plant-Based Proteins: Whey, Soy, Leucine, Corn, Pea 02:04:28 Processed Foods 02:11:54 Obesity Epidemic, Calorie Intake & Energy Output 02:17:33 Obesity, Sugar & Fiber, Restriction & Craving 02:25:57 Artificial Sweeteners & Blood Sugar 02:38:55 Artificial Sweeteners & Gut Microbiome, Sucralose, Blood Sugar 02:50:19 Rapid Weight Loss, Satiety & Beliefs 02:58:13 Seed Oils & Obesity, Saturated Fat, Overall Energy Toxicity 03:08:15 Females, Diet, Exercise & Menstrual Cycles 03:14:05 Raw vs. Cooked Foods 03:16:32 Berberine & Glucose Scavenging 03:19:12 Fiber & Gastric Emptying Time 03:21:00 Supplements, Creatine Monohydrate, Rhodiola Rosea 03:30:33 Hard Training; Challenge & Mental Resilience 03:36:12 Carbon App 03:47:11 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Disclaimer: https://hubermanlab.com/disclaimer

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grégoire_louis 1 month ago

this video had that rare i’ll just check it for a sec energy and somehow ended up keeping me hooked the entire time 😂🔥

keith.mitchell
keith.mitchell 2 months ago

As someone who has dropped 25kg in weight from obese to healthy. The identity piece really resonated with me as when I was younger I completely changed my life around, and part of the reason was from the theories of addiction where you need to become someone new. If you are overweight, don't be afriad to become a new beast for people to see :)!

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rael.novaes 5 months, 1 week ago

I’m blown away by how good this tutorial is!

lakshmiatlas43
lakshmiatlas43 5 months, 3 weeks ago

I am someone who lost 70 lbs. and have maintained that loss for 40+ years. I did so addressing it, with support, as an addiction. I lost and maintain via eating three moderate whole food meals per day with nothing in between. The "nothing in between" aspect became a great relief for me as it removed the monkey off my back, the voice that created a decision point in each consecutive moment. The "moderate" piece came initially with weighing and measuring all food; today it's pretty automatic. I believe there are metabolic liver pathways related to addiction, and for the compulsive overeater, it is very important not to eat an amount of food at any point that triggers the out-of-control mechanism in the liver (relative to an alcoholic taking that first drink). Once that line is crossed, one tends to lose control and that can be very difficult to retrieve. There exists the belief that one is always an addict relative to their particular substance. But after decades of practice, this doesn't seem to be the case for me. It is natural for me at this point to eat moderately, and I often eat only two meals in a day as opposed to three, without bother. Perhaps this information will be helpful and hopeful for others who struggle with this issue.

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meghana_bobal 6 months, 1 week ago

It’s crazy how much easier fitness gets once you understand the science instead of chasing trends.

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rolando_zayas 7 months ago

As a scientist, I really appreciate Norton's approach. I always question my experiment results and try to view them in a larger context. Also, when reading scientific literature, you may come across a very questionable methodology, and sometimes legitimate study limitations, especially with studies about nutrition. So everything should be taken with a grain of salt. Personally, I don't listen to people who absolutely KNOW what they are talking about and trust people who are more careful of making definitive statements. As i learned throughout the years at this profession, you "dont know", more than you "know". in short, I like this guy.

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saanvi.sha 11 months, 1 week ago

A few weeks ago, I was chatting with a friend about how manifesting never seemed to work for me. I’d tried so many methods but still felt stuck. We heard about a book called Manifest and Receive by Eva Hartley on a podcast, and I was hesitant at first. But after reading just a few chapters, I realized how much I was missing. Eva's approach is so different from anything I’ve ever tried. It’s not just about thinking positive, it’s about aligning with real-world actions that bring your desires into reality. Now, I’ve manifested opportunities I never imagined possible, and my mindset has shifted completely. If you’re frustrated like I was, don’t hesitate. Read this book. It will change everything ❤

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rafaél_gastélum 1 year ago

I always wondered how different diets affect metabolism, and Dr. Norton's insights on plant-based proteins were enlightening. Makes me appreciate brands like LyfeFuel that focus on clean, sustainable nutrition.

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martinemarion431 1 year ago

This is the best on most reasonable discussion about diet I've ever heard. Layne seems like a great guy.

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allenanderson404 1 year, 2 months ago

Fiber and microbiomes fascinate the heck outta me! As a mom to a son with Pettigrew syndrome/Parkinson's/autism and ADHD (the ADHD from me), his whole life (23yrs old) a huge focus has been gut health and nutrition and seeing connections in his growth/behavior/ and physical changes based on what we are eating etc. Fiber has been a huge marker in his behavioural and mental aspects! We are using a phgg protein but including in extra prebiotics. Regular bathroom habits, as well as glucose regulation =steadier moods, more focus.

matthewmist72
matthewmist72 1 year, 9 months ago

I first discover layne norton in the bodybuilding world over 10 years ago and he keeps getting better

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liabeier261 1 year, 10 months ago

Thank you for watching. If you enjoyed this topic and episode, please click the "like" button and subscribe to our channel here on YouTube. Thank you for your interest in science! -- Andrew

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daniel_garcia 2 years, 4 months ago

🎯 Key Takeaways for quick navigation: 00:00 Dr. *Layne Norton is an expert in nutrition, protein metabolism, muscle gain, and fat loss.* 00:27 The *discussion covers various topics in nutrition and fitness, including energy balance, artificial sweeteners, gut health, fasting, protein needs, different diets, and supplements.* 08:33 Calories *are units of energy derived from macronutrients in food, mainly through the production of ATP in the body.* 15:23 Energy *balance involves tracking calories in (food intake) and calories out (resting metabolic rate, physical activity, thermic effect of food, and non-exercise activity thermogenesis or NEAT).* 19:11 NEAT *(non-exercise activity thermogenesis) plays a significant role in energy expenditure, and it involves spontaneous physical activity like fidgeting, which can contribute to maintaining leanness.* 21:34 A *classic study from 1995 showed that in a metabolic ward, people who overate by 1,000 calories a day for six weeks gained weight and fat mass. However, some individuals gained more than expected, while one person gained just over 1/2 a kilo due to spontaneous increased physical activity.* 23:22 Non-Exercise *Activity Thermogenesis (NEAT) is the most modifiable factor among BMR (Basal Metabolic Rate), TEF (Thermic Effect of Food), and NEAT. A 10% reduction in body weight can lead to a decrease of almost 500 calories a day in NEAT.* 26:34 Fitness *trackers often overestimate energy expenditure, which can lead to misconceptions about calorie intake and weight loss.* 32:40 The *specific form of exercise chosen can affect appetite differently for individuals, but it's important to remember that beliefs and suggestions about exercise can also influence its effects.* 39:17 The *power of suggestion and beliefs can have significant physiological effects, even on substances like creatine, highlighting the importance of mindset and expectations in how supplements and interventions work.* 42:07 Exercise *can have an appetite suppressant effect, and it may not always lead to full compensation for calories burned, making it valuable for weight management.* 45:52 Exercise *likely affects appetite regulation at the brain level rather than just blood sugar, and it can make individuals more sensitive to satiety signals.* 48:19 Weight *loss maintenance is challenging because people often focus on the initial weight loss without considering long-term strategies. The key is finding a sustainable diet and lifestyle that an individual can adhere to in the long run.* 52:03 Successful *weight loss maintainers often mention developing a new identity as a crucial aspect of their journey, emphasizing the importance of mindset and behavioral change in maintaining weight loss.* 01:02:39 Providing *food to study participants can lead to higher adherence in nutrition studies compared to free-living studies.* 01:03:08 Low *carb versus low fat diets show no significant difference in fat loss when protein and calories are equated, allowing individuals to choose the dietary approach that suits them best.* 01:04:05 Switching *between dietary approaches, such as going from keto to omnivore, can be a reasonable strategy as long as portion control and calorie goals are maintained.* 01:05:28 Transitioning *from a low carb to a higher carb diet may result in a temporary period of insulin resistance, but it is typically not a long-term concern.* 01:07:49 Transitioning *out of a ketogenic diet should be done gradually over four to eight weeks to avoid discomfort during the adjustment period.* 01:08:48 Gut *health plays a role in metabolism, and there is ongoing research on the gut-brain axis and its impact on appetite regulation.* 01:10:16 Fiber *is essential for gut health, and dietary fiber acts as a prebiotic, positively impacting the gut microbiota.* 01:16:50 Consuming *fiber-rich foods, including fruits, vegetables, whole grains, and cereals, can support gut health and longevity.* 01:22:33 Some *evidence suggests that saturated fat, combined with bile end products, may have a negative effect on certain beneficial gut microbiota strains.* Protein is *a significant lever for various health goals.* Consuming around *1.6 grams of protein per kilogram of body weight is a good target for most people.* Higher protein *intake can lead to increased calorie burn due to its higher thermic effect of food.* Protein helps *preserve lean body mass during a diet, build it in maintenance, and support it in a surplus.* The satiety *effects of protein can vary depending on individual foods, and not all high-protein foods are equally satiating.* 01:43:29 Satiety *depends on the type of carbohydrate; plain baked potatoes are highly satiating.* 01:44:26 Concerns *about the 30-gram protein per meal limit may not be necessary; protein distribution matters, but total daily protein intake is crucial.* 01:47:40 Muscle *protein synthesis may not be significantly impacted by protein distribution in moderate fasting protoco

kerry_nicholson
kerry_nicholson 2 years, 4 months ago

This is honestly one of my favorite episodes. I don’t know how this wasn’t a 5+hr discussion. I could listen to him for hours and I have so many questions left haha well done yall

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graciela_morales 2 years, 5 months ago

Videos like this are helping me so much in my bulimia recovery, thank you for putting this resource out there in such an easily accessible way

keith_davis
keith_davis 2 years, 5 months ago

It's crazy how knowledgeable and cutting edge in research your guests consistently reflect in their expertise and it always becomes obvious that you're probably one of the few people that can understand, translate for us plebes and keep up with them at any given moment. Another amazing interview.

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aprilclark960 2 years, 5 months ago

This is a very good podcast, speaking on artificial sweeteners. I use to take metformin haven't taken for almost 10 years. I lost 67 lbs using artificial sweeteners and a reduce carbs in my meals walking/resistance training and fasting for 16 hours. It took me almost a year and a half. My pain has totally gone away, migraines/Gerd/as well. I am still working on it and want to get to a good weight my weight was 267 now 196. The one thing I learned was as soon as I stop eating every two hours as recommended by my dietitian and only having one carb per meal ranging roughly 50-60. I sometimes look at the glycemic index of food now that I have learned . I have also learned that I don't need to increase the amount of added fat; keeps my body from burning its body fat. Once I start to feel full I now stop never happened before, Again thank you so very much.

priya_ghose
priya_ghose 2 years, 6 months ago

Function of Self- this was an incredible eye opener to me. You're so right about doing good for others. Like I used to like to pay for the next person's toll, just hoping to improve their mood for the moment. They can't even thank me that way! They have to completely enjoy it. 😉

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robert.maldonado 2 years, 6 months ago

I keep finding myself thanking people on these podcasts, but here I go again! I've been sporadically weighing myself and getting really upset when I gain after losing. I did it again tonight, not thinking about how I drank more water tonight! Plus it's colder now, so my clothes weigh more. Gonna start trying your ideas

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ethan.santos 2 years, 7 months ago

I came across Layne around 15 years ago he really knows his stuff. I had forgotten about him as I am not in that industry in the way I was back the. This is probably my favourite episode of this podcast.